|Printable version||E-mail this to a friend|
BHF - Common prescription painkillers linked to increased risk of heart failure
A study has found that commonly used prescribed painkillers, used to treat pain and inflammation, are associated with an increased risk of hospitalisation for heart failure.
The drugs include traditional non-steroidal anti-inflammatory drugs (NSAIDs) as well as new generation anti-inflammatory drugs, known as COX-2 inhibitors.
Previous studies have shown an association between use of traditional NSAIDs and COX 2 inhibitors and an increased risk of heart failure, but this research, published today in The BMJ, set out to estimate the risk of hospital admission for heart failure with use of individual NSAIDs.
The team of researchers, led by Giovanni Corrao at the University of Milano-Bicocca in Italy, looked at almost 10 million NSAIDs users from four European countries including the UK.
Current use of any NSAID was found to be associated with a raised risk of hospital admission for heart failure, compared with past use.
The researchers found that the magnitude of risk varied between individual NSAIDs and according to the dose prescribed. At very high doses, risk of admission for heart failure doubled for some NSAIDs.
What BHF think of the research
BHF Medical Director, Professor Peter Weissberg, said:
"This large observational study reinforces previous research showing that some NSAIDs, a group of drugs commonly taken by patients with joint problems, increase the risk of developing heart failure.
"It has been known for some years now that such drugs need to be used with caution in patients with, or at high risk of, heart disease. This applies mostly to those who take them on a daily basis rather than only occasionally.
"Since heart and joint problems often coexist, particularly in the elderly, this study serves as a reminder to doctors to consider carefully how they prescribe NSAIDs, and to patients that they should only take the lowest effective dose for the shortest possible time. They should discuss their treatment with their GP if they have any concerns."
Latest News from
Cancer Research UK - One-off bowel scope cuts cancer risk for at least 17 years23/02/2017 09:35:00
A one-off bowel screening test reduces the risk of developing bowel cancer by more than one third and could save thousands of lives, according to a study published in The Lancet
Cancer Research UK - Lifetime weight gain linked to oesophageal and stomach cancers16/02/2017 15:35:00
People who are overweight in their twenties and become obese later in life may be three times more likely to develop cancer of either the oesophagus (food pipe) or upper stomach, according to a study published in the British Journal of Cancer on Wednesday.
Age UK - 'Borrowed time' to save social care system from collapse16/02/2017 11:35:00
A new report from Age UK has concluded that we are living on borrowed time to save the social care system for older people.
Cancer Research UK - NHS cancer treatment target in England missed for third consecutive year14/02/2017 12:35:00
The ’62 day’ waiting time target for cancer patients in England has been missed again, marking 3 years since the target was last met.