National Institute for Health and Clinical Excellence (NICE)
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NICE, PHE and SACN publish rapid COVID-19 guidance on vitamin D

NICE, PHE and SACN yesterday published rapid guidance on vitamin D for COVID-19

In collaboration with Public Health England (PHE), and the Scientific Advisory Committee on Nutrition (SACN), NICE conducted a rapid evidence review evaluating evidence from recent studies on vitamin D in relation to COVID-19.

The expert panel supported current government advice for everyone to take the supplement throughout the autumn and winter, however the panel concluded that there is currently not enough evidence to support taking vitamin D solely to prevent or treat COVID-19.

The data reviewed by the panel includes the best available scientific evidence published so far, including both observational studies and randomised controlled trials. However, it was not possible to determine a direct relationship between vitamin D and COVID-19 based on the available evidence.

Due to the lack of reliable evidence on the effects of the supplement on COVID-19, our guidance recommends that more research be conducted on the subject, stressing the use of high-quality randomised controlled trials in future studies.

Dr Paul Chrisp, director of the Centre for Guidelines at NICE, said: “While there is insufficient evidence to recommend vitamin D for the prevention or treatment of COVID-19 at this time, we encourage people to follow government advice on taking the supplement throughout the autumn and winter period.

“As research continues on the impact of vitamin D on COVID-19, we are continuing to monitor evidence as it is published and will review and update the guidance if necessary.”

The new guidance states that people should continue to follow the current government advice on daily vitamin D supplementation to maintain bone and muscle health during the COVID-19 pandemic.

Professor Ian Young, Chair of the Scientific Advisory Committee on Nutrition, which advises PHE and other UK government organisations on nutrition and related health matters, said: “SACN has worked closely with NICE and PHE to consider the available evidence from recent studies on vitamin D in relation to COVID-19. This evidence review confirms that currently there is not enough available evidence to determine that there is a causal relationship between vitamin D and COVID-19.”

It is recommended that everyone should take a daily 10 microgram (400 international units) vitamin D supplement from October to early March. This dose is safe and effective at maintaining healthy vitamin D blood levels.

Vitamin D is required for the maintenance of healthy bone and muscle. Although sunlight exposure is the major source of vitamin D for most people during summer months, it can also be obtained from the diet or supplements.

Many people have been indoors more than usual this spring and summer, which means we might not have been making enough vitamin D from sunlight. So, it’s even more important this year to take a vitamin D supplement as we go into the winter months.

Some people are more at risk of not having enough vitamin D even in spring and summer, including those with dark skin (such as those with African, African-Caribbean or south Asian backgrounds), those who are not outdoors often, those in care homes, and those who cover up most of the skin when outdoors. We advise these people to take a vitamin D supplement all year round. Clinically vulnerable groups will also be eligible for free vitamin D supplements throughout the winter period, starting in January.

Dr Alison Tedstone, chief nutritionist at Public Health England, said: “Vitamin D is important for our bone and muscle health.

“We advise that everyone, particularly the elderly, those who don’t get outside and those with dark skin, takes a vitamin D supplement containing 10 micrograms (400IU) every day.

“This year, the advice is more important than ever with more people spending more time inside.”

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