Food Standards Agency
Peanut allergies affected by exercise and sleep deprivation, new study finds
FSA funded research has found that exercise and sleep deprivation can put people with a peanut allergy at greater risk of a reaction.
Sleep deprivation and exercise can make people with peanut allergies more sensitive, a study at Addenbrooke’s Hospital has found.
Published in The Journal of Allergy and Clinical Immunology, the team found that exercise and sleep deprivation each significantly reduce the threshold of reactivity (the amount of peanut needed to trigger a reaction) in people with peanut allergy, putting them at greater risk of a reaction.
Led by the allergy research team at Addenbrooke’s, and funded by The Food Standards Agency (FSA), the TRACE study is hugely significant, as one in every 100 adults and one in every 50 children, have peanut allergies - the most common cause of fatal allergic reactions.
Allergies remains an under-researched subject and the FSA has targeted support for projects which aim to progress our knowledge in this area. These findings will pave the way for better food labelling and greater understanding of the factors that can lead to allergic reactions.
Dr Shelley Dua, lead investigator at Addenbrooke’s, yesterday said:
“Precautionary allergen labels on food such as the commonly used ‘May contain traces of...’ are currently quite vague and not very helpful. This is partly because until now we simply haven't known enough about the amount of allergen which causes a reaction and how day to day factors like tiredness and exercise affect allergic reactions.
This study takes us a long way towards building that knowledge and changing the way we label allergens making life easier and safer for allergic individuals.”
The Food Standards Agency Chair, Heather Hancock yesterday said:
“The FSA commissioned and funded this ground-breaking research because we want to significantly improve the understanding of everyday impacts that can contribute to an allergic reaction.
“This is vital work and can help us redefine how foods are labelled in future, so that people can manage their allergies more safely.
“It’s impossible to remove the allergy risk for people, but these findings give us essential evidence. In future, it could support precautionary allergen labelling so people will know exactly when a food poses a real risk to them which can increase the trust they have in their food.”
The work, which could be applied to other foods, reveals that exercise, sleep deprivation or stress significantly reduce the amount of peanut required to cause an allergic reaction.
It provides cut-off levels appropriate for the UK population which longer-term could help regulators and the food industry develop accurate evidence-based food labelling – keeping consumers safe and enabling greater variety of diet.
Patient Lynsey Brown, who participated in the research, yesterday said:
“The TRACE study really helped me to understand how much peanut I can eat before I develop a reaction. I’m so glad that this important research is being done to help address the issue of food labelling which is real day-to-day problem for me.”
More than 126 peanut allergic individuals took part in the trial. Participants were given a peanut challenge where they were given increasing amounts of peanut flour to eat until they developed an allergic reaction which was treated quickly. This challenge was repeated when they were exercising and when they were sleep-deprived.
Dr Andrew Clark, of the CUH allergy support team and chief investigator, described the TRACE study as a “team effort” with the National Institute for Health Research/Welcome Trust Cambridge Clinical Research Facility (Cambridge UK), Royal Brompton& Harefield NHS Foundation Trust Clinical Research Facility (London) and the University of Manchester all contributing.
He yesterday said:
“I would like to thank all those who have supported this significant piece of research, including our peanut allergic participants and sponsors.
“While the development of new labelling will likely take some time, the immediate benefit is that we can raise awareness among sufferers the consequence of stress, sleep deprivation and exercise can have on tolerance of peanut.”
Since 2013 The FSA has funded more than £5.7 million of research projects into allergens.
This has included groundbreaking work on role of the skin barrier, timing and introduction of allergens in the infant diet, how older children are affected by food allergy and linkages between early life nutrition and development of allergic diseases.
About Cambridge University Hospitals (CUH)
Cambridge University Hospitals NHS Foundation Trust (CUH) is one of the largest and best known trusts in the country, delivering high-quality patient care through Addenbrooke’s and the Rosie Hospitals. CUH is a leading national centre for specialist treatment for rare or complex conditions and a university teaching hospital with a worldwide reputation.
Latest News from
Food Standards Agency
FSA consults on updated guidance following change to allergen labelling law24/01/2020 10:20:00
The FSA has published a consultation on updates to its existing technical guidance to reflect changes to food allergen labelling legislation in England which comes into effect on 1 October 2021.
Belfast Trust Achieves Calorie Wise Gold Award23/01/2020 08:15:00
The Belfast Health and Social Care Trust is recognised with a Calorie Wise Gold Award for displaying calorie information on all menu items in restaurants across five of its hospital sites.
FSA Board: ‘Protecting the consumer interest comes first’22/01/2020 14:10:00
The Food Standards Agency (FSA) Board yesterday confirmed its approach to future trade negotiations featuring food and feed, contributed to the development of the National Food Strategy, and signed off a long-term strategy to improve life for people with allergies and intolerances.
Open Meeting of Welsh Food Advisory Committee14/01/2020 14:10:00
The Welsh Food Advisory Committee of the Food Standards Agency is holding its next open meeting in Cardiff on Thursday 16 January 2020.
FSA Board meeting papers published for January 202010/01/2020 11:42:00
The agenda and papers for the January Board meeting have been published.
New appointments to the FSA Board08/01/2020 10:10:10
The Food Standards Agency has announced three new appointments to its Board. Margaret Gilmore, Timothy Riley and Mark Rolfe will serve for three-year terms, ending in 2022.
Reduce food waste and stay safe this Christmas18/12/2019 10:10:00
We buy approximately 10 million turkeys each Christmas, yet we throw away over 100,000 tonnes of poultry every year, most of it completely edible.
FSA Chair elected Master of St John’s College Cambridge05/12/2019 14:10:00
The Chairman of the Food Standards Agency, Heather Hancock, has been elected as the new Master of St John’s College, Cambridge. Heather will take up her post in October next year.
FSA Social Science Symposium centres on food, innovation and the future consumer06/11/2019 15:20:00
Lab grown meat, the perspectives of Generation Z, climate change and the impact of space technology on the food system were some of the topics discussed at our third annual Symposium of Social Science.