Science and Technology Facilities Council
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New knowledge will boost fight against superbug

A breakthrough in the fight against drug-resistant infections is one step closer following the discovery of the structure of NDM-1: a vicious bacterial bug that is resistant to the most powerful antibiotics currently available.

Medical Research Council (MRC) scientists at the Research Complex at Harwell (RCaH) in Oxfordshire, have produced a model of NDM-1: a model that will now enable researchers and pharmaceutical companies to progress towards potential new treatments.

The research is published today in the online journal Acta Crystallographica Section F: Structural Biology and Crystallization Communications.

STFC is a partner in the Research Complex at Harwell.

More information can be found in the Medical Research Council’s Press Release (link opens in a new window).

Further information:

For a copy of the paper or to arrange an interview with the researcher, please contact the MRC Press Office on 0207 395 2345 or email

The Research Complex at Harwell (RCaH) is a government-funded, state-of-the-art science facility for researchers on the Harwell Science and Innovation Campus in Oxfordshire. The RCaH provides a unique environment for researchers in the life and physical sciences, enabling them to work in synergy at the interface between traditional disciplines and use the major facilities on the Harwell Campus such as ISIS and the Diamond Light synchrotron. The Medical Research Council lead the RCaH project on behalf of Research Councils UK, in partnership with the BBSRC, EPSRC, NERC, STFC and Diamond Light Source.

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